Professor Mateo Aboy

Prof. Mateo Aboy is Director of Research in Technology & Law (Biomedical Innovation, AI/QC & Law) at the University of Cambridge, UK. He is a member of the Centre for Law, Medicine & Life Sciences (LML) and the Centre for IP & Information Law (CIPIL) at Cambridge, as well as Inter-CeBIL (Copenhagen-Cambridge-Harvard International Collaborative Program in Biomedical Innovation & Law). He is also a Fellow at the Stanford Center for Responsible Quantum Technology.

His multidisciplinary background includes a combination of engineering, law, regulatory science, and management experience. He holds degrees in electrical & computer engineering (BS, BSEE, MSECE, MPhil/DEA, PhD ECE), law (SJD/PhD/LLD), and international management (MBA), as well as professional registrations as a Professional Chartered Engineer (CEng, EU/ES COIT), Certified Licensing Professional (CLP), Patent Practitioner with a Bar Admission/licensed to practice in patent cases before the United States Patent Office (USPTO), Fellow of Information Privacy (IAPP Fellow, FIP), Certified Privacy Information Professional (CIPP/E), Certified Privacy Manager (CIPM), Lead Implementer of Information Security Management Systems-ISMS (ISO 27001), Lead Auditor of Medical Device Quality Management Systems (ISO 13485), Lead Implementer of Privacy Information Management Systems - PIMS (ISO 27701), and Certified Data Protection Officer (C-DPO).

His research investigates the intersection of digital innovation, IP policy and economics of healthcare by exploring the key tenets of innovation with a focus on the digital health, biotech, and pharmaceutical industries. This includes investigating the transformation of medical technology, drug development and healthcare delivery, as well as the associated legal, regulatory, policy and strategy questions raised by the growth of medical AI/ML/QC and biotech innovations for personalised medicine. Mateo’s research seeks to understand the drivers of technology-based innovation, IP incentives, and the determinants of how emergent medical technologies are protected, regulated, funded, developed, adopted and used in practice.

Mateo pursues research at the interface between technology, law, and innovation. His research ranges from biomedical signal processing (BSP) and R&D of novel medical devices to evidence-based IP studies of precision medicine and information age inventions (biomarkers, diagnostics, and algorithm/AI-based inventions), medical device regulation, information security, and data protection law.

He is the author of more than 150 scholarly articles published in leading scientific, engineering and legal journals, including Nature Biotechnology, IEEE Transactions of Biomedical Engineering, Medical and Biological Engineering & Computing, Medical Engineering & Physics, Journal of Law & the Biosciences, International Review of Intellectual Property and Competition Law (IIC), and Journal of Intellectual Property Law & Practice.

His professional experience includes work in various senior roles both in the private sector and academia. As a Licensed Patent Practitioner, he has successfully prosecuted numerous cases before the USPTO, focusing primarily on medical device and computer-implemented inventions. He holds over 20 patents as an inventor and is the co-founder of APDM Wearable Technologies, Inc (acquired by ERT/Clario).

Mateo has taught university courses in engineering (computational data science; scientific & engineering computation; digital signal processing; electronics; programming; research methods & innovation), law (IP law, patent law; business law), and management (strategy, innovation, and entrepreneurship; engineering management).

Selected Publications

Prof. Aboy's scholarly publications include:

1. Aboy, M., Druedahl, L. C., & Minssen, T. (2023). Evidence-based IP research. In Research Handbook on Empirical Studies in Intellectual Property Law (pp. 120-136). Edward Elgar Publishing. doi:10.4337/9781802206210.00013
2. Aboy, M., Price, W. N., & Raker, S. (2023). Mapping the patent landscape of medical machine learning.. Nature Biotechnology, 41(4), 461-468. doi:10.1038/s41587-023-01735-6
3. Laal, S., Vasilyev, P., Pearson, S., Aboy, M., & McNames, J. (2022). Feasibility of Tracking Human Kinematics with Simultaneous Localization and Mapping (SLAM).. Sensors (Basel), 22(23). doi:10.3390/s22239378
4. Liddicoat, J., Liddell, K., Darrow, J., Aboy, M., Jordan, M., Crespo, C., & Minssen, T. (2022). Repositioning Generic Drugs: Empirical Findings and Policy Implications. IIC International Review of Intellectual Property and Competition Law, 53(9), 1287-1322. doi:10.1007/s40319-022-01241-3
5. Kop, M., Aboy, M., & Minssen, T. (2022). Intellectual property in quantum computing and market power: a theoretical discussion and empirical analysis. Journal of Intellectual Property Law and Practice, 17(8), 613-628. doi:10.1093/jiplp/jpac060
6. Sagar, A., Liddell, K., Liddicoat, J., & Aboy, M. (2022). Patent eligibility and precision medicine: Emerging technologies, legal flux and empirical methods. In Patenting Biotechnical Innovation: Eligibility, Ethics and Public Interest (pp. 19-42).
7. Aboy, M., Minssen, T., & Kop, M. (2022). Mapping the Patent Landscape of Quantum Technologies: Patenting Trends, Innovation and Policy Implications. IIC International Review of Intellectual Property and Competition Law, 53(6), 853-882. doi:10.1007/s40319-022-01209-3
8. Aboy, M., Liddell, K., Jordan, M., Crespo, C., & Liddicoat, J. (2022). European patent protection for medical uses of known products and drug repurposing.. Nature Biotechnology, 40(4), 465-471. doi:10.1038/s41587-022-01269-3
9. Corrales Compagnucci, M., Aboy, M., & Minssen, T. (n.d.). Cross-Border Transfers of Personal Data After Schrems II: Supplementary Measures and new Standard Contractual Clauses (SCCs). Nordic Journal of European Law, 4(2), 37-47. doi:10.36969/njel.v4i2.23780
10. Aboy, M., Liddell, K., Liddicoat, J., Crespo, C., & Jordan, M. (2021). Mapping the European patent landscape for medical uses of known products.. Nature Biotechnology, 39(11), 1336-1343. doi:10.1038/s41587-021-01104-1
11. Liddicoat, J., Liddell, K., Aboy, M., & Wested, J. (2021). Has the EU Incentive for Drug Repositioning Been Effective? An Empirical Analysis of the “+1” Regulatory Exclusivity. IIC International Review of Intellectual Property and Competition Law, 52(7), 825-851. doi:10.1007/s40319-021-01088-0
12. Minssen, T., & Aboy, M. (n.d.). The Patentability of Computer-Implemented Simulations and Implications for Computer-Implemented Inventions (CIIs). Journal of Intellectual Property Law & Practice. doi:10.1093/jiplp/jpab098
13. Bradford, L., Aboy, M., & Liddell, K. (n.d.). Standard contractual clauses for cross-border transfers of health data after Schrems II. Journal of Law and the Biosciences, 8(1). doi:10.1093/jlb/lsab007
14. Corrales Compagnucci, M., Minssen, T., Seitz, C., & Aboy, M. (n.d.). Lost on the High Seas without a Safe Harbor or a Shield? Navigating Cross-Border Transfers in the Pharmaceutical Sector After Schrems II Invalidation of the EU-US Privacy Shield. European Pharmaceutical Law Review, 4(3), 153-160. doi:10.21552/eplr/2020/3/5
15. Bradford, L., Aboy, M., & Liddell, K. (2020). International transfers of health data between the EU and USA: a sector-specific approach for the USA to ensure an 'adequate' level of protection.. J Law Biosci, 7(1), lsaa055. doi:10.1093/jlb/lsaa055
16. Sherkow, J. S., & Aboy, M. (2020). The FDA De Novo medical device pathway, patents and anticompetition.. Nature Biotechnology, 38(9), 1028-1029. doi:10.1038/s41587-020-0653-6
17. Bradford, L., Aboy, M., & Liddell, K. (n.d.). COVID-19 Contact Tracing Apps: A Stress Test for Privacy, the GDPR and Data Protection Regimes. Journal of Law and the Biosciences. doi:10.1093/jlb/lsaa034
18. Minssen, T., Gerke, S., Aboy, M., Price, N., & Cohen, G. (n.d.). Regulatory responses to medical machine learning. Journal of Law and the Biosciences. doi:10.1093/jlb/lsaa002
19. Minssen, T., Seitz, C., Aboy, M., & Corrales Compagnucci, M. (2020). The EU-US Privacy Shield Regime for Cross-Border Transfers of Personal Data under the GDPR. European Pharmaceutical Law Review, 4(1), 34-50. doi:10.21552/eplr/2020/1/6
20. Aboy, M., Crespo, C., Liddell, K., Davey, N., Liddicoat, J., & Minssen, T. (2020). One year after Vanda, are diagnostics patents transforming into methods of treatment to overcome Mayo-based rejections?. Nature Biotechnology, 38(3), 279-283. doi:10.1038/s41587-020-0440-4
21. Liddicoat, J., Liddell, K., McCarthy, A. H., Hogarth, S., Aboy, M., Nicol, D., . . . Hopkins, M. M. (2020). Reply to C.D. Richter.. Eur J Hum Genet, 28(5), 537-538. doi:10.1038/s41431-020-0588-x
22. Aboy, M., Liddell, K., Crespo, C., Cohen, I. G., Liddicoat, J., Gerke, S., & Minssen, T. (2019). How does emerging patent case law in the US and Europe affect precision medicine?. Nature Biotechnology, 37(10), 1118-1125. doi:10.1038/s41587-019-0265-1
23. McNames, J., Shah, V. V., Mancini, M., Curtze, C., El-Gohary, M., Aboy, M., . . . Horak, F. (2019). A Two-Stage Tremor Detection Algorithm for Wearable Inertial Sensors During Normal Daily Activities.. In Annu Int Conf IEEE Eng Med Biol Soc Vol. 2019 (pp. 2535-2538). United States. doi:10.1109/EMBC.2019.8857133
24. Aboy, M., Crespo, C., Liddell, K., Minssen, T., & Liddicoat, J. (2019). Mayo's impact on patent applications related to biotechnology, diagnostics and personalized medicine.. Nature Biotechnology, 37(5), 513-518. doi:10.1038/s41587-019-0111-5
25. Liddicoat, J., Liddell, K., McCarthy, A. H., Hogarth, S., Aboy, M., Nicol, D., . . . Hopkins, M. M. (2019). Continental drift? Do European clinical genetic testing laboratories have a patent problem?. Eur J Hum Genet, 27(7), 997-1007. doi:10.1038/s41431-019-0368-7
26. Aboy, M., Crespo, C., Liddell, K., Liddicoat, J., & Jordan, M. (2018). Was the Myriad decision a 'surgical strike' on isolated DNA patents, or does it have wider impacts?. Nature Biotechnology, 36(12), 1146-1149. doi:10.1038/nbt.4308
27. Aboy, M., Liddicoat, J., Liddell, K., Jordan, M., & Crespo, C. (2017). After Myriad, what makes a gene patent claim 'markedly different' from nature?. Nature Biotechnology, 35(9), 820-825. doi:10.1038/nbt.3953
28. Vasilyev, P., Pearson, S., El-Gohary, M., Aboy, M., & McNames, J. (2017). Inertial and time-of-arrival ranging sensor fusion.. Gait Posture, 54, 1-7. doi:10.1016/j.gaitpost.2017.02.011
29. Polk, E., Polk, L., Aboy, M., & Crespo, C. (2016). Review of recent patents in the area of intelligent, adaptive, wireless and GPS enabled HVAC control devices. Recent Patents on Engineering, 10(3), 175-186. doi:10.2174/1872212110666160822123141
30. Aboy, M., Liddell, K., Liddicoat, J., & Crespo, C. (2016). $\textit{Myriad's}$ impact on gene patents. Nature Biotechnology, 34(11), 1119-1123. doi:10.1038/nbt.3719
31. Kim, S., Noor, F., Aboy, M., & McNames, J. (2016). A novel particle filtering method for estimation of pulse pressure variation during spontaneous breathing.. Biomed Eng Online, 15(1), 94. doi:10.1186/s12938-016-0214-x
32. Warlick, B., Diaz, C., Vasconcelos, P. S., Crespo, C., & Aboy, M. (2015). Review of recent patents on anaerobic digester gas for fuel cell applications. Recent Patents on Engineering, 9(2), 113-123. doi:10.2174/1872212109666150612232711
33. Diaz, C., Ponder, A. R., McGee, M., Crespo, C., & Aboy, M. (2015). Review of recent patents on carbon nanotube based electrodes for use in supercapacitor applications. Recent Patents on Engineering, 9(1), 21-28. doi:10.2174/1872212109666141219002829
34. Aboy, M., Hornero, R., Abásolo, D., & Alvarez, D. (2006). Interpretation of the Lempel-Ziv complexity measure in the context of biomedical signal analysis.. IEEE Trans Biomed Eng, 53(11), 2282-2288. doi:10.1109/TBME.2006.883696
35. McNames, J., & Aboy, M. (2006). Cardiovascular signal decomposition and estimation with the extended Kalman smoother.. In Conf Proc IEEE Eng Med Biol Soc Vol. 2006 (pp. 3708-3711). United States. doi:10.1109/IEMBS.2006.260463
36. Austin, D., Staats, C., & Aboy, M. (2006). A novel approach to pulse pressure variation estimation.. In Conf Proc IEEE Eng Med Biol Soc Vol. 2006 (pp. 1391-1393). United States. doi:10.1109/IEMBS.2006.260039
37. Smith, R., Crespo, C., & Aboy, M. (2013). Review of recent patents on flexible photovoltaic applications in portable and niche markets. Recent Patents on Engineering, 7(3), 153-166. doi:10.2174/18722121113076660004
38. Aboy, M., McNames, J., & Crespo, C. (2013). Review of recent patents on wearable movement sensors. Recent Patents on Biomedical Engineering, 6(2), 82-88. doi:10.2174/1874764711306020002
39. Aboy, M., Crespo, C., McNames, J., & Sprunger, J. (2013). Review of recent patents on detection and quantification of tremor. Recent Patents on Biomedical Engineering, 6(2), 89-96. doi:10.2174/1874764711306020003
40. Kim, S., Aboy, M., & McNames, J. (2013). Pulse pressure variation tracking using sequential Monte Carlo methods. Biomedical Signal Processing and Control, 8(4), 333-340. doi:10.1016/j.bspc.2013.01.008
41. Molina-Picó, A., Cuesta-Frau, D., Miró-Martínez, P., Oltra-Crespo, S., & Aboy, M. (2013). Influence of QRS complex detection errors on entropy algorithms. Application to heart rate variability discrimination.. Comput Methods Programs Biomed, 110(1), 2-11. doi:10.1016/j.cmpb.2012.10.014
42. Crespo, C., Fernández, J. R., Aboy, M., & Mojón, A. (2013). Clinical application of a novel automatic algorithm for actigraphy-based activity and rest period identification to accurately determine awake and asleep ambulatory blood pressure parameters and cardiovascular risk.. Chronobiol Int, 30(1-2), 43-54. doi:10.3109/07420528.2012.701147
43. Crespo, C., Aboy, M., Fernández, J. R., & Mojón, A. (2012). Automatic identification of activity-rest periods based on actigraphy.. Med Biol Eng Comput, 50(4), 329-340. doi:10.1007/s11517-012-0875-y
44. McNames, J., Kim, S., & Aboy, M. (2011). Statistical model for cardiovascular signals with independent respiratory modulation for tracking pulse pressure variation.. In Annu Int Conf IEEE Eng Med Biol Soc Vol. 2011 (pp. 4681-4684). United States. doi:10.1109/IEMBS.2011.6091159
45. Marcos, J. V., Hornero, R., Álvarez, D., Aboy, M., & Del Campo, F. (2012). Automated prediction of the apnea-hypopnea index from nocturnal oximetry recordings.. IEEE Trans Biomed Eng, 59(1), 141-149. doi:10.1109/TBME.2011.2167971
46. Molina-Picó, A., Cuesta-Frau, D., Aboy, M., Crespo, C., Miró-Martínez, P., & Oltra-Crespo, S. (2011). Comparative study of approximate entropy and sample entropy robustness to spikes.. Artif Intell Med, 53(2), 97-106. doi:10.1016/j.artmed.2011.06.007
47. Marcos, J. V., Hornero, R., Alvarez, D., Del Campo, F., & Aboy, M. (2010). Automated detection of obstructive sleep apnoea syndrome from oxygen saturation recordings using linear discriminant analysis.. Med Biol Eng Comput, 48(9), 895-902. doi:10.1007/s11517-010-0646-6
48. Cannesson, M., Aboy, M., Hofer, C. K., & Rehman, M. (2011). Pulse pressure variation: where are we today?. In J Clin Monit Comput Vol. 25 (pp. 45-56). Netherlands. doi:10.1007/s10877-010-9229-1
49. El-Gohary, M., McNames, J., Chung, K., Aboy, M., Salarian, A., & Horak, F. (2010). Continuous At-Home Monitoring of Tremor in Patients with Parkinson's Disease. In ANALYSIS OF BIOMEDICAL SIGNALS AND IMAGES (pp. 420-424). Retrieved from https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000303723700073&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=940c5db9f6a527ba8e12659dac275555
50. Micó, P., Mora, M., Cuesta-Frau, D., & Aboy, M. (2010). Automatic segmentation of long-term ECG signals corrupted with broadband noise based on sample entropy.. Comput Methods Programs Biomed, 98(2), 118-129. doi:10.1016/j.cmpb.2009.08.010
51. Cuesta-Frau, D., Varela, M., Aboy, M., & Miró-Martínez, P. (2009). Description of a portable wireless device for high-frequency body temperature acquisition and analysis.. Sensors (Basel), 9(10), 7648-7663. doi:10.3390/s91007648
52. Aboy, M., Crespo, C., & Austin, D. (2009). An enhanced automatic algorithm for estimation of respiratory variations in arterial pulse pressure during regions of abrupt hemodynamic changes.. IEEE Trans Biomed Eng, 56(10), 2537-2545. doi:10.1109/TBME.2009.2024761
53. Holland, A., & Aboy, M. (2009). A novel recursive Fourier transform for nonuniform sampled signals: application to heart rate variability spectrum estimation.. Med Biol Eng Comput, 47(7), 697-707. doi:10.1007/s11517-009-0461-0
54. Cuesta-Frau, D., Aboy, M., & Biagetti, M. (2009). Response: Can a simulation study of T-wave alternans (TWA) resolve whether TWA is T-wave amplitude dependent?. Medical and Biological Engineering and Computing, 47(3), 355. doi:10.1007/s11517-009-0442-3
55. Kim, S., Aboy, M., & McNames, J. (2009). Pulse pressure variation estimation using a sequential Monte Carlo method.. In Annu Int Conf IEEE Eng Med Biol Soc Vol. 2009 (pp. 5713-5716). United States. doi:10.1109/IEMBS.2009.5332663
56. Cuesta-Frau, D., Miro-Martinez, P., Oltra-Crespo, S., Varela-Entrecanales, M., Aboy, M., Novak, D., & Austin, D. (2009). Measuring body temperature time series regularity using Approximate Entropy and Sample Entropy.. In Annu Int Conf IEEE Eng Med Biol Soc Vol. 2009 (pp. 3461-3464). United States. doi:10.1109/IEMBS.2009.5334602
57. Cuesta-Frau, D., Micó-Tormos, P., Aboy, M., Biagetti, M. O., Austin, D., & Quinteiro, R. A. (2009). Enhanced modified moving average analysis of T-wave alternans using a curve matching method: a simulation study.. Med Biol Eng Comput, 47(3), 323-331. doi:10.1007/s11517-008-0415-y
58. Staats, C., Austin, D., & Aboy, M. (2008). A statistical model and simulator for cardiovascular pressure signals.. Proc Inst Mech Eng H, 222(6), 991-998. doi:10.1243/09544119JEIM348
59. Zhang, Z. G., Tsui, K. M., Chan, S. C., Lau, W. Y., & Aboy, M. (2008). A novel method for nonstationary power spectral density estimation of cardiovascular pressure signals based on a Kalman filter with variable number of measurements.. Med Biol Eng Comput, 46(8), 789-797. doi:10.1007/s11517-008-0351-x
60. Hornero, R., Aboy, M., Gómez, C., Hagg, D. S., & Phillips, C. R. (2008). Complexity analysis of arterial pressure during periods of abrupt hemodynamic changes.. IEEE Trans Biomed Eng, 55(2 Pt 1), 797-801. doi:10.1109/TBME.2007.901037
61. McNames, J., & Aboy, M. (2008). Statistical modeling of cardiovascular signals and parameter estimation based on the extended Kalman filter.. IEEE Trans Biomed Eng, 55(1), 119-129. doi:10.1109/TBME.2007.910648
62. Cuesta-Frau, D., Biagetti, M., Micó-Tormos, P., Aboy, M., & Quinteiro, R. (2007). T-wave alternans analysis improvement by means of curve alignment prior to distance calculation.. In Annu Int Conf IEEE Eng Med Biol Soc Vol. 2007 (pp. 690-693). United States. doi:10.1109/IEMBS.2007.4352384
63. Aboy, M., Cuesta-Frau, D., Austin, D., & Micó-Tormos, P. (2007). Characterization of sample entropy in the context of biomedical signal analysis. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 5942-5945). doi:10.1109/IEMBS.2007.4353701
64. Ellis, T., McNames, J., & Aboy, M. (2007). Pulse morphology visualization and analysis with applications in cardiovascular pressure signals.. IEEE Trans Biomed Eng, 54(9), 1552-1559. doi:10.1109/TBME.2007.892918
65. Sánchez, C. I., Hornero, R., López, M. I., Aboy, M., Poza, J., & Abásolo, D. (2008). A novel automatic image processing algorithm for detection of hard exudates based on retinal image analysis.. Med Eng Phys, 30(3), 350-357. doi:10.1016/j.medengphy.2007.04.010
66. Cuesta, D., Varela, M., Miró, P., Galdós, P., Abásolo, D., Hornero, R., & Aboy, M. (2007). Predicting survival in critical patients by use of body temperature regularity measurement based on approximate entropy.. Med Biol Eng Comput, 45(7), 671-678. doi:10.1007/s11517-007-0200-3
67. Hornero, R., Aboy, M., & Abásolo, D. (2007). Analysis of intracranial pressure during acute intracranial hypertension using Lempel-Ziv complexity: further evidence.. Med Biol Eng Comput, 45(6), 617-620. doi:10.1007/s11517-007-0194-x
68. Vinecore, K., Aboy, M., McNames, J., Phillips, C., Agbeko, R., Peters, M., . . . Goldstein, B. (2007). Design and implementation of a portable physiologic data acquisition system.. Pediatr Crit Care Med, 8(6), 563-569. doi:10.1097/01.PCC.0000288715.66726.64
69. Aboy, M., Cuesta-Frau, D., Austin, D., & Mico-Tormos, P. (2007). Characterization of sample entropy in the context of biomedical signal analysis.. Annu Int Conf IEEE Eng Med Biol Soc, 2007, 5943-5946. doi:10.1109/IEMBS.2007.4353701
70. Cuesta-Frau, D., Biagetti, M. O., Quinteiro, R. A., Micó-Tormos, P., & Aboy, M. (2007). Unsupervised classification of ventricular extrasystoles using bounded clustering algorithms and morphology matching.. Med Biol Eng Comput, 45(3), 229-239. doi:10.1007/s11517-006-0118-1
71. McNames, J., & Aboy, M. (2006). Reliability and accuracy of heart rate variability metrics versus ECG segment duration.. Med Biol Eng Comput, 44(9), 747-756. doi:10.1007/s11517-006-0097-2
72. McNames, J., & Aboy, M. (2006). Cardiovascular Signal Decomposition and Estimation with the Extended Kalman Smoother. In 2006 International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE. doi:10.1109/iembs.2006.4398254
73. Aboy, M., Fernández, J. R., & Hermida, R. C. (2006). The population RDH index: a novel vector index and graphical method for statistical assessment of antihypertensive treatment reduction, duration, and homogeneity.. Blood Press Monit, 11(3), 143-155. doi:10.1097/01.mbp.0000209089.85858.52
74. Aboy, M., & Falkenberg, J. H. (2006). An automatic algorithm for stationary segmentation of extracellular microelectrode recordings.. Med Biol Eng Comput, 44(6), 511-515. doi:10.1007/s11517-006-0052-2
75. Aboy, M., Fernández, J. R., McNames, J., & Hermida, R. C. (2006). The individual RDH index: a novel vector index for statistical assessment of antihypertensive treatment reduction, duration, and homogeneity.. Blood Press Monit, 11(2), 69-78. doi:10.1097/01.mbp.0000209070.07837.45
76. Hornero, R., Abásolo, D., Jimeno, N., Sánchez, C. I., Poza, J., & Aboy, M. (2006). Variability, regularity, and complexity of time series generated by schizophrenic patients and control subjects.. IEEE Trans Biomed Eng, 53(2), 210-218. doi:10.1109/TBME.2005.862547
77. Hornero, R., Aboy, M., Abasolo, D., McNames, J., Wakeland, W., & Goldstein, B. (2006). Complex analysis of intracranial hypertension using approximate entropy.. Crit Care Med, 34(1), 87-95. doi:10.1097/01.ccm.0000190426.44782.f0
78. Austin, D., Staats, C., & Aboy, M. (2006). A novel approach to pulse pressure variation estimation. In 2006 28TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-15 (pp. 2436-+). Retrieved from https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000247284702190&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=940c5db9f6a527ba8e12659dac275555
79. Hornero, R., Aboy, M., Abásolo, D., McNames, J., & Goldstein, B. (2005). Interpretation of approximate entropy: analysis of intracranial pressure approximate entropy during acute intracranial hypertension.. IEEE Trans Biomed Eng, 52(10), 1671-1680. doi:10.1109/TBME.2005.855722
80. Aboy, M., McNames, J., Thong, T., Tsunami, D., Ellenby, M. S., & Goldstein, B. (2005). An automatic beat detection algorithm for pressure signals.. IEEE Trans Biomed Eng, 52(10), 1662-1670. doi:10.1109/TBME.2005.855725
81. Aboy, M., Márquez, O. W., McNames, J., Hornero, R., Trong, T., & Goldstein, B. (2005). Adaptive modeling and spectral estimation of nonstationary biomedical signals based on Kalman filtering.. IEEE Trans Biomed Eng, 52(8), 1485-1489. doi:10.1109/TBME.2005.851465
82. Aboy, M., Fernández, J. R., & Hermida, R. C. (2005). Methodological considerations in the evaluation of the duration of action of antihypertensive therapy using ambulatory blood pressure monitoring.. Blood Press Monit, 10(3), 111-115. doi:10.1097/00126097-200506000-00001
83. Aboy, M., McNames, J., Wakeland, W., & Goldstein, B. (2005). Pulse and mean intracranial pressure analysis in pediatric traumatic brain injury.. In Acta Neurochir Suppl Vol. 95 (pp. 307-310). Austria. doi:10.1007/3-211-32318-x_63
84. Novák, D., Lhotská, L., Cuesta-Frau, D., Micó, P., Al-Ani, T., Hamam, Y., & Aboy, M. (2004). Morphology analysis of physiological signals using Hidden Markov Models. In Proceedings - International Conference on Pattern Recognition Vol. 3 (pp. 754-757). doi:10.1109/ICPR.2004.1334638
85. Novák, D., Cuesta-Frau, D., Al ani, T., Aboy, M., Mico, P., & Lhotská, L. (2004). Speech recognition methods applied to biomedical signals processing.. In Conf Proc IEEE Eng Med Biol Soc Vol. 2006 (pp. 118-121). United States. doi:10.1109/IEMBS.2004.1403105
86. Aboy, M., McNames, J., Márquez, O., Hornero, R., Thong, T., & Goldstein, B. (2004). Power spectral density estimation and tracking nonstationary pressure signals based on Kalman filtering.. In Conf Proc IEEE Eng Med Biol Soc Vol. 2006 (pp. 156-159). United States. doi:10.1109/IEMBS.2004.1403115
87. Thong, T., McNames, J., & Aboy, M. (2004). Lomb-Wech periodogram for non-uniform sampling.. In Conf Proc IEEE Eng Med Biol Soc Vol. 2006 (pp. 271-274). United States. doi:10.1109/IEMBS.2004.1403144
88. McNames, J., Thong, T., & Aboy, M. (2004). Impulse rejection filter for artifact removal in spectral analysis of biomedical signals.. In Conf Proc IEEE Eng Med Biol Soc Vol. 2006 (pp. 145-148). United States. doi:10.1109/IEMBS.2004.1403112
89. Thong, T., Yung, I. O., P Zajdel, D. P., Ellingson, R. M., McNames, J., Aboy, M., & Oken, B. S. (2004). Heart rate variability analysis of effect of nicotine using periodograms.. In Conf Proc IEEE Eng Med Biol Soc Vol. 2006 (pp. 294-297). United States. doi:10.1109/IEMBS.2004.1403150
90. Aboy, M., McNames, J., Hornero, R., Thong, T., Cuesta, D., Novak, D., & Goldstein, B. (2004). A novel statistical model for simulation of arterial and intracranial pressure.. In Conf Proc IEEE Eng Med Biol Soc Vol. 2006 (pp. 129-132). United States. doi:10.1109/IEMBS.2004.1403108
91. Aboy, M., McNames, J., Thong, T., Phillips, C. R., Ellenby, M. S., & Goldstein, B. (2004). A novel algorithm to estimate the pulse pressure variation index deltaPP.. IEEE Trans Biomed Eng, 51(12), 2198-2203. doi:10.1109/TBME.2004.834295
92. Segura-Juárez, J. J., Cuesta-Frau, D., Samblas-Pena, L., & Aboy, M. (2004). A microcontroller-based portable electrocardiograph recorder.. IEEE Trans Biomed Eng, 51(9), 1686-1690. doi:10.1109/TBME.2004.827539
93. Thong, T., McNames, J., Aboy, M., & Goldstein, B. (2004). Prediction of paroxysmal atrial fibrillation by analysis of atrial premature complexes.. IEEE Trans Biomed Eng, 51(4), 561-569. doi:10.1109/TBME.2003.821030
94. Aboy, M., McNames, J., Cuesta-Frau, D., Wakeland, W., Thong, T., Lai, S., & Goldstein, B. (2003). Significance of Intracranial Pressure Pulse Morphology in Pediatric Traumatic Brain Injury. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings Vol. 3 (pp. 2491-2494).
95. Falkenberg, J. H., McNames, J., Aboy, M., & Burchiel, K. J. (2003). Segmentation of Extracellular Microelectrode Recordings with Equal Power. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings Vol. 3 (pp. 2475-2478).
96. Aboy, M., McNames, J., Thong, T., Phillips, C. R., Ellenby, M. S., & Goldstern, B. (2003). Pulse Pressure Variation Estimation Based on Rank-Order Filters. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings Vol. 3 (pp. 2435-2438).
97. Thong, T., McNames, J., Aboy, M., & Goldstein, B. (2003). Paroxysmal Atrial Fibrillation Prediction Using Isolated Premature Atrial Events and Paroxysmal Atrial Tachycardia. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings Vol. 1 (pp. 163-166).

For more of Prof. Aboy's publications, see here.

Selected Patents

Prof. Aboy's granted patents as an inventor include:

• US 8,920,345 System and apparatus for continuous monitoring of movement disorders
• US 8,647,287 Wireless synchronized movement monitoring apparatus and system
• US 8,926,521 Method for blood pressure measurement from noninvasive oscillometric pressure signals
• US 7,927,283 Blood pressure algorithm
• US 8,900,153 Ambulatory patient monitoring apparatus, system and method
• US 8,315,698 Method and apparatus for automatic analysis of T-wave alternans
• US 8,305,423 Communication system for remote patient visits and clinical status monitoring
• US 8,057,398 Method, system, and apparatus for cardiovascular signal analysis, modeling, and monitoring
• US 8,529,458 Method and apparatus for assessment of fluid responsiveness
• US 8,298,151 Method and apparatus for evaluation of fluid responsiveness
• US 8,647,287 Method and system for activity/rest identification
• US 8,862,195 Method, system, and apparatus for automatic detection of obstructive sleep apnea from oxygen saturation recording

For more of Prof. Aboy's patent publications see here.

Selected Presentation & Reports

• "ELSPI Implications of Quantum Technologies", Centre for Quantum & Society (Amsterdam), September 2023

• "Advanced Medical Computing, AI & Quantum Technologies", CeBIL Conference, June 2022

• "Mapping the European Patent Landscape for Medical Uses of Known Products", CeBIL Conference, June 2021

• "Beyond the FDA 501(k): An Analysis of the De Novo Classification Pathway for Medical Devices", CeBIL Conference, June 2021

• "The FDA De Novo Medical Device Pathway, Patents & Anticompetition", CeBIL Conference 2021

• "International Transfers of Health Data Between the EU and USA", CeBIL Conference 2021

• "The Patentability of Biotech and Precision Medicine Inventions: Subject Matter Eligibility of Gene-Related Patents, Biomarkers, Diagnostics & Algorithms for Personalised Medicine", University of Salamanca, April 2020

• "Is the Recent Patent Case-Law "Good" for Precision Medicine", CIPIL Anual Spring Conference, March 2020

• "Are Algorithms Patentable?The Subject Matter Eligibility of Algorithms & Computer-Implemented Inventions" PHG Workshop-Regulating algorithms in healthcare: intellectual property and liability,September 2018

• "Precision Medicine, AI and the Law Impact of Myriad, Mayo & Alice" 2018 CeBIL Annual Symposium, Precision Medicine, Artificial Intelligence and the Law, September 2018

• “Myriad’s Impact on Gene Patents. Lessons Learned from Empirical Studies” CeBIL Conference-Innovation Gaps in the Life Sciences Frontiers, March, 2018.

• “Should We Change the EU Law to Disallow DNA Patents? Aboy M. 3rd Annual Philomathia Symposium (2016)

• “Analysis of the Impact of the US Supreme Court decision Mayo v Prometheus” Aboy M. Workshop on Realizing Genomic Medicine (2016),